Subvalvular Gradients in Patients With Valvular Aortic Stenosis

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Subvalvular gradients in patients with valvular aortic stenosis: prevalence, magnitude, and physiological importance.

BACKGROUND Although subvalvular gradients in patients with aortic stenosis have been described, their behavior and response to exercise have not been well characterized. METHODS AND RESULTS Left ventricular and aortic pressures and linear flow velocity were measured with a catheter-tip manometer at rest and during supine exercise in 27 patients with valvular aortic stenosis. A subvalvular gra...

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Fluid dynamics of aortic stenosis: subvalvular gradients without subvalvular obstruction.

Analysis of a tapering, pulsatile flow field predicts that substantial subvalvular pressure gradients exist in patients with valvular aortic stenosis (AS) without invoking a second anatomic site of obstruction. Using a catheter with two laterally mounted micromanometers, we examined the left ventricle in 11 patients with AS, mean age 64 +/- 11 years (+/- SD); the mean valve area was 1.0 +/- 0.3...

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Subvalvular Aortic Stenosis.

Subvalvular aortic stenosis (SAS) is a congenital heart defect that causes fixed form of hemodynamically significant left ventricular outflow tract (LVOT) obstruction with progressive course. It has a spectrum of anatomy. It appears usually beyond infancy, causes left ventricular hypertrophy and myocardial dysfunction, and tends to involve the aortic and mitral valves in its progressive course....

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[Subvalvular aortic stenosis associated with 8p23 deletion].

We report the case of a 35-year-old man admitted due to heart failure, who had had moderate cognitive deficit, craniofacial dysmorphism, epilepsy, panic attacks and congenital heart disease (subvalvular aortic stenosis) associated with chronic atrial fibrillation since childhood. In view of his facial dysmorphism and clinical presentation, karyotype analysis was performed and revealed a de novo...

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Echocardiographic findings in discrete subvalvular aortic stenosis.

Echographic features of three patients with discrete subvalvular aortic stenosis are presented. These include a narrowed area of the left ventricular outflow tract just below the aortic valve cusps in all cases. A high-intensity but thin echo was seen in the high left ventricular outflow tract at the level of the mitral annulus in one patient with a subaortic diaphragm. In one of the three pati...

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ژورنال

عنوان ژورنال: Circulation

سال: 2001

ISSN: 0009-7322,1524-4539

DOI: 10.1161/hc3401.095041